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Calamintha bactica, Origonum vulgaris and Cuminum cyminum have been studied for their capacities as a source of antifungal compounds. One set of these plants grown under water stress. The other set of plants was submitted to different mineral nutrition. The plant material obtained after grinding, were extracted with MeOH or EtOAc, fractionated with organic solvents, and tested for their antifungal properties. Cladosporium cucumerinum and several Fusarium strains were used as biological targets. NMR was used for studying the metabolites content of C. baetica produced under either watering or mineral stress conditions.