DOMINGUES, Joana [et al.] (2023) - Essential oils of two Portuguese endemic species of lavandula as a source of antifungal and antibacterial sgents. Processes. 11, 1165. DOI https:// doi.org/10.3390/pr11041165
cv-prod-3230846
10.3390/pr11041165
Title
Essential oils of two portuguese endemic species of lavandula as a source of antifungal and antibacterial agents
Subject
L. stoechas subsp. luisieri L. pedunculata Chemical profile Antimicrobial activity Cytotoxicity
Chemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were
analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated
from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the
MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential
oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%),
while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity
of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it
ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and
MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial
activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability)
in NHDF cells at all concentrations tested. info:eu-repo/semantics/publishedVersion
